STRATEGY OF DEVELOPING NUCLEIC ACID-BASED UNIVERSAL MONKEYPOX VACCINE CANDIDATES



MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

Mutations in genes encoding components of chromatin modifying and remodeling complexes are among the most frequently observed somatic events in human cancers.For example, missense and nonsense mutations targeting the mixed lineage leukemia family member Pouch 3 (MLL3, encoded by KMT2C) histone methyltransferase occur in a range of solid tumors, and

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Epidemiology of cardiovascular disease and its risk factors among refugees and asylum seekers: Systematic review and meta-analysis

Background: This is the first systematic review and meta-analysis assessing cardiovascular disease incidence and risk factors among refugees and asylum seekers.Methods and results: PubMed, PsycINFO, CINAHL, and Embase databases were searched for studies in English from January 1, 1977, to March 8, 2020.Inclusion criteria were (1) observation of ref

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Dosimetric comparison between conventional and conformal radiotherapy for carcinoma cervix: Are we treating the right volumes?

Background and Purpose: Conventional portals, based on bony anatomy, for external beam radiotherapy for cervical cancer have been repeatedly demonstrated as inadequate.Conversely, with image-based conformal radiotherapy, better target coverage may be offset by the greater toxicities and poorer compliance associated with treating larger volumes.This

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